Coinbase Advanced
The most regulated crypto exchange in the US. Best-in-class institutional custody and unmatched regulatory clarity for US-based investors.
Cold StorageProof of ReservesStakingDeFi Access
4.5/ 5
Best Crypto Exchanges with DeFi Integration
Last updated
5
Exchanges
Each broker on this page has been chosen for its integration with decentralized finance, allowing traders to access DeFi protocols and assets directly via the platform. Quality in this category requires on-chain wallet connectivity, support for trading major DeFi tokens like UNI, AAVE, and MKR with minimum order sizes as low as $10, and the ability to interact with protocols such as Uniswap and Compound without withdrawal limits. Traders should check that the broker publishes daily smart contract audit reports and maintains cold storage coverage exceeding 90 percent of user assets to mitigate DeFi-specific risks.
Top DeFi Integration Exchanges
5 crypto exchangesSort:
Unmatched liquidity and coin selection. The go-to exchange for active crypto traders despite ongoing regulatory complexity in some jurisdictions.
Cold StorageProof of ReservesStakingDeFi AccessBest-in-class for CeFi/DeFi integration. The strongest platform for traders who want both exchange trading and on-chain DeFi access in a single interface.
Cold StorageProof of ReservesStakingDeFi Access- Cold StorageProof of ReservesStakingDeFi AccessCold StorageProof of ReservesStaking
What this means
DeFi (Decentralised Finance) integration allows you to access on-chain lending, liquidity provision, yield farming, and DApp ecosystems directly through the exchange interface, without managing a separate wallet or handling gas fees manually. This hybrid CeFi/DeFi model reduces the technical barrier to accessing on-chain yield while maintaining the familiar security model of a regulated exchange.
Related Features
Frequently Asked Questions
When comparing exchanges for DeFi Integration, prioritise regulatory standing, security architecture (cold storage, Proof of Reserves), and fee transparency. Our list ranks exchanges by overall rating across all these criteria.
We currently list 5 crypto exchanges with DeFi Integration. The full list above is sortable by rating and other criteria.
Safety depends primarily on the exchange’s security architecture, not the feature itself. Always choose exchanges that maintain cold storage, publish Proof of Reserves, and hold recognised regulatory licences before using any product.
Regulation varies by exchange. All exchanges in our list display their primary regulatory authority. Always verify an exchange's licence status directly on the regulator's official register before depositing funds.
Choose an exchange from the list above, click through to their full profile, and review their fees, regulatory standing, and security features. Most exchanges support multiple device types and offer guided onboarding for new users.